I can start the game, select "new game", select a race, select advanced settings, but when I hit "start game" it tells "DBGHELP.DLL is too old" and then dies. It's on Steam autopatch and I did an integrity check and the game is all up to date. I found DBGHELP.DLL in c:\windows\system32 and it's from 2010, and probably thus the factory standard for Win 7. Steam says the game supports older versions of Windows like XP and Vista, but I find that unlikely anymore.
This change is recentish - I played a lot last year(*) (97 hours, all achievable achievements earned), and was just coming back to it to see how the patches changed the game and to get myself psyched for the DLC.
I can provide more info on request.
(*) or whenever the super ship/androids patch came out. I've played with those.